Introduction for Ampoule bottles’ Headspace Analysis Detection Methods

Ampoule bottle’s headspace analysis (especially the residual oxygen analysis ) related to the quality stability of powder-injection, water injection, infusion bottle and oral liquid in product warranty period. Through Labthink’s HGA-01 Headspace gas analyzer and its dedicated sampler can conveniently and efficiently solve the residual oxygen detection problem and make small-volume ampoule bottle and other packaging detecting achieve good result.

1.Why we must control ampoule bottle’s residual oxygen content of the headspace gas

Oxygen is the main factor to influence the product warranty period of powder injection, water injection and oral liquid. It was found that by control the gas proportion of the packaging can effectively prolong the product shelf life or improve the reservation quality. Nowadays some products’ packages such as powder injection, water injection and oral liquid, mainly adopt ampoule bottle’s packaging way.  After filling there will be a little gas remaining in the bottle, So the actual gas composite in the package bottle is different from expected, which take some difficulty in analyzing product quality, expected validity of warranty life and rationality of the packaging design .By HGA-01 Headspace Gas Analyzer produced by Labthink can effectively solve the gas composition problem in ampoule bottle. Now it had become an important means to check the drug design’s quality and one of the important ways to verify the product warranty.

2. Detecting difficulties in ampoule bottle’s Headspace gas analysis



Amboule Bottle



Residual oxygen is an important point in headspace gas analysis, but the integral volume of common ampoule bottle package such as powder injection, water injection and oral liquid is small, and the headspace gas volume of ampoule bottle is less. The common headspace analyzing equipment can’t carry the analyzing test of gas collection amount which is less than 0.5ml and 0.2ml.And this is also the detecting difficulty of headspace gas analyzer for small volume packaging such as ampoule bottles.

3. Choose the appropriate Headspace Gas Analyzer HGA-01

Now some headspace gas analyzer on the market basically cannot complete the residual oxygen analysis of water injection and powder injection and other medicine.HGA-01 Headspace Gas Analyzer produced by Labthink can solve the above difficulties through the specialized sampler, which can make small package headspace gas analysis detection realized.HGA-01 Headspace Gas Analyzer absorb the advantage of desktop and portable equipment, and also have many unique advantages. Firstly, It can test oxygen and dioxide simultaneously, while the range and accuracy reach to the first-class in the international world. Secondly, it has annual and automatic operating mode and test oxygen and dioxide in the meantime.

Configure dedicated needle，gaskets and filters, get great improvement in exhaust time and response time ,which can totally ensure the reality and effectiveness of the testing data.
In addition, the instrument is equipped with the current international mainstream gas analyzer sensors, which can guarantee six years normal use. To facilitate the instrument have the portable and  hand function, and have the printing function which the traditional equipment don’t have ，which can make it conveniently used in various environments and have rapid detection for the sample.

4. Ampoule bottle residual oxygen analysis detection summary



HGA-01 Headspace Gas Analyzer



The detection analysis for the headspace gas residual oxygen can make us control the packaging change of internal gas component for powder-injection, water-injection and oral liquid more conveniently, accurately and rapidly, and also the important data support for analysis of product quality, effectiveness of shelf life and rationality of packaging design and be an essential testing ways to strengthen the product quality control, the practical and reliable HGA-01 Headspace Gas Analyzer with dedicated procurement sampler equipment is the basis to have residual analysis control for more pharmaceutical companies.

More about the detailed information for pharmaceutical headspace gas analyzer, pls contact Emily for 0531-85060139 or go on the web: www.labthink.cn for inquiry.

Water Vapor Transmission Rate Test for Solar Backsheet

 With the development and usage of the renewable energy, along with the advocation and encourage of National policy, Solar backsheet,as a relatively mature cleaning energy, has been more and more used in industrial production and daily life. Solar modules are sequently laminated by solar PV glass, EVA,  solar cells and solar backsheet. As the most outermost protective layer of the solar cell module, solar battery backsheet plays an important protecting and supporting role to battery piece and to be an important component of solar cell module. The service life of solar cell products is generally long .In order to meet the requirement, the backsheet material must not only have good weather resistance, shock resistance and reliable insulativity, but also have the higher water barrier performance. If the solar backsheet had the bad water barrier performance, then the humidity in air((especially rainy days more moisture) will pass through solar backsheet to inner side, and will affect the bonding properties of EVA  and result in the backsheet separating from EVA, and more moisture vapor directly contact with solar cells and make the cell oxidation, thus affecting the battery life. So the barrier performance is an important indicator to measure the performance of solar cell backsheet .It mainly reflected in the water vapor transmission rate data. The smaller the water vapor transmission rate, the better the water resistance.

Next, We will have some simple introduction to solar backsheet ‘s water vapor permeation test combined with Labthink PERMETM W3/330 water vapor transmission rate testing system.



Water Vapor Transmission Rate Tester



 Water vapor transmission rate is the quality of water vapor through the unit area in unit time，which is determined by the material’s barrier properties and the water vapor concentration of the material. Currently, Japan’s Sharp, Kyocera all have clear requirement to backssheet’s water vapor transmission rate indicator. Germany, Austria and other countries have the clear standard. Nowadays, most clients in the industry had generally adopt water vapor transmission rate testing principle of electrolysis method because its high-accuracy and good reliability.   

Labthink’s R&D production W3/330 Water vapor transmission rate testing system ,adopting electrolysis test principle, structure design and excellent selection of components to make equipment with higher testing accuracy. and the control ability of temperature and humidity of environment is much higher than standard requirement, and provide a convenient and rapid calibration method as well.  By the Patent cavity structure  design, the instrument can complete three kinds of same or different specimens test simultaneously, while using the host machine and satellite machine mode, a host can connect 9 satellite. which can achieve a maximum of 30 samples simultaneously to satisfy the testing demand for large laboratory test. And its application range is wide, which is suitable for water vapor transmission rate testing for plastic film. composite membrane, sheet material, high barrier materials, backplane, metal foil, waterproofing membrane, fabric, rubber, building materials ,the carton cardboard and solar backsheet.


W3/330 WVTR Tester



While ensure the index of water vapor transmission rate of solar backsheet is standard, we must have control other indicators such as tensile strength and peel strength to ensure the quality of the products .About more information of the testing instrument, please see more details at www.labthink.cn .Labthink Instruments Co.,Ltd hopes to have further cooperation with the enterprises in all industry.
Detailed,pls contact Emily at trade12#labthink.cn or the telephone:0086-531-85060139.